Functional Gastrointestinal Disorders: Recognition of Clinical Features and Progress of Understanding of Pathological Patterns

Clinical Features and Pathogenesis of FGIDs

Abstract

Functional gastrointestinal disorders (FGIDs) is almost the most common diseases in the outpatient department of gastroenterology. However, patients with different FGIDs often have different symptoms and severity. Gastroenterologists not only need to distinguish it from other diseases, but also to refine the classification of functional gastrointestinal diseases in order to obtain the greatest therapeutic benefit for the FGIDs patients. The pathophysiology of functional gastrointestinal disorders is sophisticated, which leads to complex clinical manifestations. The latest theoretical hypotheses and research focus on altered brain-gut axis, intestinal microecology, GI mucosal immunity, and GI neuroendocrine,  it will help us have a deeper understanding of the pathogenesis and pathophysiology of FDIDs.